Course options
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Qualification
PhD/DPhil - Doctor of Philosophy
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Location
The University of Manchester
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Study mode
Full time
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Start date
01-SEP-25
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Duration
3 years
Course summary
Programme description
Our PhD/MPhil Pharmacology programme enables you to undertake a research project that will improve understanding of Pharmacology.
Our pharmacology research focuses on a range of topics. These include:
- the pharmacology of drug efflux transporters, particularly ABCB1 P-glycoprotein, ABCG2 breast cancer resistance protein and ABCC multidrug resistance-associated transporters;
- developing complex, physiologically-relevant in vitro cell systems to investigate transport, metabolism and delivery of therapeutic drugs;
- understanding the pharmacological and molecular mechanisms that regulate expression and function of drug efflux transporters, particularly in the blood-brain barrier;
- the role of blood-brain barrier drug efflux transporters in drug delivery to the central nervous system and the effects of inflammatory and degenerative conditions, eg Alzheimer's disease, on efflux transporter function;
- the biological role of lipid networks in health and disease, particularly their roles in inflammation, cellular communications and tissue responses;
- employing mass spectrometry-based lipidomic technology, in conjunction with functional, metabolic and signaling approaches to characterise lipid profiles in physiological and pathophysiological conditions;
- investigating the role of lipids in skin homeostasis and in response to inflammation, injury and wound healing;
- studying role of local hormones in diseases and conditions associated with the female reproductive tract (eg dysmenorrhoea, endometriosis and the detection and prevention of preterm labour);
- molecularly identifying and pharmacologically characterising receptors expressed in the female reproductive system;
- understanding the physiological and pharmacological characteristics of the placenta. These studies include the development of placental homing peptide-microRNA inhibitor conjugates for targeted enhancement of placental growth signaling.
Teaching and learning
PhD/MPhil programmes are based on individual research projects that last three to four years (PhD) or one year (MPhil), working with a specific Primary Supervisor and Co-Supervisor(s).
Applicants are specifically matched with a Primary Supervisor and individual project based on their research interests and background.
Career opportunities
Your postgraduate research degree will open up a range of career opportunities after you graduate.
Tuition fees
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£ 27,000per year
Tuition fees shown are for indicative purposes and may vary. Please check with the institution for most up to date details.
University information
University of Manchester
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University League Table
22nd
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Campus address
The University of Manchester, Oxford Road, Manchester, Manchester, M13 9PL, England
Subject rankings
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Subject ranking
13th out of 45 4
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Entry standards
/ Max 228161 70%13th
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Graduate prospects
/ Max 10090.0 90%19th
4 -
Student satisfaction
/ Max 42.95 74%35th
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