51ÊÓƵ

We address key questions in the fundamental biology of ageing, animal welfare and food security. How and why does ageing occur and what are its impacts on health and well-being? How do animals cope with pollutants? How do we achieve sustainable animal production whilst protecting animal health and welfare?

Students will also achieve iPhD exit awards during this course.

OVERVIEW

Individual research projects are tailored around the expertise of principal investigators within the Institutes. A variety of approaches are used, including experiments in field and laboratory conditions, epidemiology, mathematical, computational and statistical modelling, bioinformatics, physiology, molecular biology, parasitology, immunology and polyomics (genomics, transcriptomics, proteomics, metabolomics). Basic and applied science projects are available for study, as are field-based projects with research programs underway in both the UK and overseas.

Ageing affects almost all species, but the rate at which it occurs varies considerably among and within species. People are now living much longer than previous generations, with ageing being the major risk factor for many diseases. This has given rise to the concept of not only our ‘life span’ but also our ‘health span’ which is the length of a disease free life. We know that the environment we live in can influence how we age. It is now increasingly recognised that the ageing process and its' associated disease risk can be ‘set up’ or programmed by events experienced before we are born, ‘prenatal programming’, or during postnatal development i.e. pre and peripubertal as well as in adult life. Consequently, understanding why we age, how we age, the factors responsible for variation in ageing and longevity, and the impact ageing has on health and wellbeing is a major challenge in science today.

We are uniquely placed to employ a highly integrative, comparative and collaborative approach for the study of ageing, health and animal welfare. We study ageing at the molecular, cellular and organism level, in the field and in the laboratory, and combine mechanistic, functional and applied perspectives. We currently use a range of interventions and techniques to examine key issues in both laboratory and field settings. Using these approaches we are interested in a range of factors (e.g. stress, pollution, chronobiology, diet, growth pattern, metabolism, reproduction, epidemiology, immunity), how they are affected by ageing and their impact on human and animal health.